William Dall’Acqua: шукати на сайті Z-Library

British Journal of Haematology

Рік:

2020

Мова:

english

Файл:

PDF, 4.67 MB

english, 2020

A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo

Elizabeth Ward, Nanette Mittereder, Ellen Kuta, Gary P. Sims, Michael A. Bowen, William Dall’Acqua, Thomas Tedder, Peter Kiener, Anthony J. Coyle, Herren Wu, Bahija Jallal, Ronald Herbst

Журнал:

Рік:

2011

Мова:

english

Файл:

PDF, 984 KB

english, 2011

MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Kolbeck, Roland, Kozhich, Alexander, Koike, Masamichi, Peng, Li, Andersson, Cecilia K., Damschroder, Melissa M., Reed, Jennifer L., Woods, Robert, Dall'Acqua, William W., Stephens, Geoffrey L., Erjefa

Журнал:

Journal of Allergy and Clinical Immunology

Рік:

2010

Мова:

english

Файл:

PDF, 1.17 MB

english, 2010

Tag-on-Demand: exploiting amber codon suppression technology for the enrichment of high-expressing membrane protein cell lines

Britton, Zachary T, London, Timothy B, Carrell, Jeffrey, Dosanjh, Bhupinder, Wilkinson, Trevor, Bowen, Michael A, Wu, Herren, Dall’Acqua, William F, Marelli, Marcello, Mazor, Yariv

Журнал:

Protein Engineering Design and Selection

Рік:

2019

Мова:

english

Файл:

PDF, 1.05 MB

english, 2019

Substrate-assisted catalysis: Molecular basis and biological significance

William Dall'Acqua, Paul Carter

Журнал:

Protein Science

Рік:

2000

Мова:

english

Файл:

PDF, 1.03 MB

english, 2000

A Mutational Analysis of the Binding of Two Different Proteins to the Same Antibody†

Dall'Acqua, William, Goldman, Ellen R., Eisenstein, Edward, Mariuzza, Roy A.

Журнал:

Xavier Ysern, Barry A. Fields, T.Narayan Bhat, Fernando A. Goldbaum, William Dall'Acqua, Frederick P. Schwarz, Roberto J. Poljak, Roy A. Mariuzza

Рік:

1996

Мова:

english

Файл:

PDF, 462 KB

english, 1996

Solvent Rearrangement in an Antigen—Antibody Interface Introduced by Site-directed Mutagenesis of the Antibody Combining Site

Журнал:

Bradford C. Braden, Barry A. Fields, Xavier Ysern, Fernando A. Goldbaum, William Dall'Acqua, Frederick P. Schwarz, Roberto J. Poljak, Roy A. Mariuzza

Рік:

1994

Файл:

PDF, 275 KB

1994

Crystal Structure of the Complex of the Variable Domain of Antibody D1.3 and Turkey Egg White Lysozyme: A Novel Conformational Change in Antibody CDR-L3 Selects for Antigen

Журнал:

Bradford C. Braden, Barry A. Fields, Xavier Ysern, William Dall'Acqua, Fernando A. Goldbaum, Roberto J. Poljak, Roy A. Mariuzza

Рік:

1996

Мова:

english

Файл:

PDF, 355 KB

english, 1996

Crystal Structure of an Fv–Fv Idiotope–Anti-idiotope Complex at 1.9 Å Resolution

Журнал:

Li Peng, Vaheh Oganesyan, Melissa M. Damschroder, Herren Wu, William F. Dall'Acqua

Рік:

1996

Мова:

english

Файл:

PDF, 1.17 MB

english, 1996

Structural and Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody

Журнал:

Melissa M. Damschroder, Lusiana Widjaja, Parkash S. Gill, Valery Krasnoperov, Weidong Jiang, William F. Dall’Acqua, Herren Wu

Рік:

2011

Мова:

english

Файл:

PDF, 2.85 MB

english, 2011

Framework shuffling of antibodies to reduce immunogenicity and manipulate functional and biophysical properties

Журнал:

Molecular Immunology

Рік:

2007

Мова:

english

Файл:

PDF, 896 KB

english, 2007

Structural characterization of a mutated, ADCC-enhanced human Fc fragment

Vaheh Oganesyan, Melissa M. Damschroder, William Leach, Herren Wu, William F. Dall’Acqua

Журнал:

Molecular Immunology

Рік:

2008

Мова:

english

Файл:

PDF, 1.27 MB

english, 2008

Structural characterization of a human Fc fragment engineered for extended serum half-life

Vaheh Oganesyan, Melissa M. Damschroder, Robert M. Woods, Kimberly E. Cook, Herren Wu, William F. Dall’Acqua

Журнал:

Molecular Immunology

Рік:

2009

Мова:

english

Файл:

PDF, 1.15 MB

english, 2009

Humanized antibodies and their applications

Herren Wu, William F. Dall’Acqua

Журнал:

Methods

Рік:

2005

Мова:

english

Файл:

PDF, 73 KB

english, 2005

Antibody humanization by framework shuffling

William F. Dall’Acqua, Melissa M. Damschroder, Jingli Zhang, Robert M. Woods, Lusiana Widjaja, Julie Yu, Herren Wu

Журнал:

Methods

Рік:

2005

Мова:

english

Файл:

PDF, 592 KB

english, 2005

Antibody engineering

William Dall'Acqua, Paul Carter

Журнал:

Current Opinion in Structural Biology

Рік:

1998

Мова:

english

Файл:

PDF, 858 KB

english, 1998

Contribution of Domain Interface Residues to the Stability of Antibody C H 3 Domain Homodimers

Dall'Acqua, William, Simon, Alexander L., Mulkerrin, Michael G., Carter, Paul

Журнал:

Bradford C. Braden, William Dall'Acqua, Edward Eisenstein, Barry A. Fields, Fernando A. Goldbaum, Emilio L. Malchiodi, Roy A. Mariuzza, Frederick P. Schwarz, Xavier Ysern, Roberto J. Poljak

Рік:

1998

Мова:

english

Файл:

PDF, 163 KB

english, 1998

Protein motion and lock and key complementarity in antigen-antibody reactions

Журнал:

Pharmaceutica Acta Helvetiae

Рік:

1995

Мова:

english

Файл:

PDF, 587 KB

english, 1995

Structure and Thermodynamics of Antigen Recognition by Antibodies

BRADFORD C. BRADEN, ANA CAUERHFF, WILLIAM DALL'ACQUA, BARRY A. FIELDS, FERNANDO A. GOLDBAUM, EMILIO L. MALCHIODI, ROY A. MARIUZZA, ROBERTO J. POLJAK, FREDERICK P. SCHWARZ, XAVIER YSERN, T. N. BHAT

Журнал:

Annals of the New York Academy of Sciences

Рік:

1995

Мова:

english

Файл:

PDF, 696 KB

english, 1995

A Mutational Analysis of Binding Interactions in an Antigen−Antibody Protein−Protein Complex †

Dall'Acqua, William, Goldman, Ellen R., Lin, Wenhong, Teng, Connie, Tsuchiya, Daisuke, Li, Hongmin, Ysern, Xavier, Braden, Bradford C., Li, Yili, Smith-Gill, Sandra J., Mariuzza, Roy A.

Журнал:

Oganesyan, Vaheh, Damschroder, Melissa M., Cook, Kimberly E., Li, Qing, Gao, Changshou, Wu, Herren, Dall'Acqua, William F.

Рік:

1998

Мова:

english

Файл:

PDF, 131 KB

english, 1998

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms

Журнал:

Fernando A. Goldbaum, C. Alejandro Velikovsky, William Dall'Acqua, Carlos A. Fossati, Barry A. Fields, Bradford C. Braden, Roberto J. Poljak and Roy A. Mariuzza

Рік:

2014

Мова:

english

Файл:

PDF, 3.67 MB

english, 2014

Characterization of Anti-Anti-Idiotypic Antibodies that Bind Antigen and an Anti-Idiotype

Журнал:

Proceedings of the National Academy of Sciences

Рік:

1997

Мова:

english

Файл:

PDF, 1.18 MB

english, 1997

Hydrogen Bonding and Solvent Structure in an Antigen−Antibody Interface. Crystal Structures and Thermodynamic Characterization of Three Fv Mutants Complexed with Lysozyme †,#

Fields, Barry A., Goldbaum, Fernando A., Dall'Acqua, William, Malchiodi, Emilio L., Cauerhff, Ana, Schwarz, Frederick P., Ysern, Xavier, Poljak, Roberto J., Mariuzza, Roy A.

Журнал:

Goldman, Ellen R., Dall'Acqua, William, Braden, Bradford C., Mariuzza, Roy A.

Рік:

1996

Мова:

english

Файл:

PDF, 1.06 MB

english, 1996

Analysis of Binding Interactions in an Idiotope−Antiidiotope Protein−Protein Complex by Double Mutant Cycles †

Журнал:

Рік:

1997

Мова:

english

Файл:

PDF, 297 KB

english, 1997

Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression

Buchanan, Andrew, Clementel, Veronica, Woods, Rob, Harn, Nicholas, Bowen, Michael A, Mo, Wenjun, Popovic, Bojana, Bishop, Steven M., Dall’Acqua, William, Minter, Ralph, Jermutus, Lutz, Bedian, Vahe

Журнал:

Рік:

2013

Мова:

english

Файл:

PDF, 1013 KB

english, 2013

Mechanisms of Neutralization of a Human Anti-α-toxin Antibody

Oganesyan, Vaheh, Peng, Li, Damschroder, Melissa M., Cheng, Li, Sadowska, Agnieszka, Tkaczyk, Christine, Sellman, Bret R., Wu, Herren, Dall'Acqua, William F.

Журнал:

Рік:

2014

Мова:

english

Файл:

PDF, 2.47 MB

english, 2014

Insights into the molecular basis of a bispecific antibody's target selectivity

Mazor, Yariv, Hansen, Anna, Yang, Chunning, Chowdhury, Partha S, Wang, Jihong, Stephens, Geoffrey, Wu, Herren, Dall’Acqua, William F

Журнал:

Рік:

2015

Мова:

english

Файл:

PDF, 1.34 MB

english, 2015

pH-dependent Binding Engineering Reveals an FcRn Affinity Threshold That Governs IgG Recycling

Borrok, M. Jack, Wu, Yanli, Beyaz, Nurten, Yu, Xiang-Qing, Oganesyan, Vaheh, Dall'Acqua, William F., Tsui, Ping

Журнал:

Oganesyan, Vaheh, Barnes, Arnita, Tkaczyk, Christine, Ferguson, Andrew, Wu, Herren, Dall'Acqua, William F.

Рік:

2015

Мова:

english

Файл:

PDF, 1.37 MB

english, 2015

Crystallization and preliminary X-ray diffraction analysis of the complex between a human anti-alpha toxin antibody fragment and alpha toxin

Журнал:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Рік:

2013

Мова:

english

Файл:

PDF, 258 KB

english, 2013

Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab

Oganesyan, Vaheh, Peng, Li, Woods, Robert M., Wu, Herren, Dall'Acqua, William F.

Журнал:

Рік:

2015

Мова:

english

Файл:

PDF, 1.37 MB

english, 2015

Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding

Borrok, M Jack, Luheshi, Nadia M, Beyaz, Nurten, Davies, Gareth C, Legg, James W, Wu, Herren, Dall'Acqua, William F, Tsui, Ping

Журнал:

Peng, Li, Damschroder, Melissa M., Cook, Kimberly E., Wu, Herren, Dall'Acqua, William F.

Рік:

2015

Мова:

english

Файл:

PDF, 1.22 MB

english, 2015

Molecular basis for the antagonistic activity of an anti-CXCR4 antibody

Журнал:

T. Narayana Bhat, Graham A. Bentley, Ginette Boulot, Mark I. Greene, Diana Tello, William Dall'Acqua, Helene Souchon, Frederick P. Schwarz, Roy A. Mariuzza and Robert J. Poljak

Рік:

2015

Мова:

english

Файл:

PDF, 2.49 MB

english, 2015

Bound Water Molecules and Conformational Stabilization Help Mediate an Antigen-Antibody Association

Журнал:

Proceedings of the National Academy of Sciences

Рік:

1994

Мова:

english

Файл:

PDF, 1.11 MB

english, 1994

Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action

Geoghegan, James C., Diedrich, Gundo, Lu, Xiaojun, Rosenthal, Kim, Sachsenmeier, Kris F., Wu, Herren, Dall'Acqua, William F., Damschroder, Melissa

Журнал:

Рік:

2016

Мова:

english

Файл:

PDF, 2.44 MB

english, 2016

A novel antibody discovery platform identifies anti-influenza A broadly neutralizing antibodies from human memory B cells

Xiao, Xiaodong, Chen, Yan, Varkey, Reena, Kallewaard, Nicole, Koksal, Adem C., Zhu, Qing, Wu, Herren, Chowdhury, Partha S., Dall'Acqua, William F.

Журнал:

Xiao, Xiaodong, Wu, Herren, Dall'Acqua, William F.

Рік:

2016

Мова:

english

Файл:

PDF, 1.91 MB

english, 2016

Immunotherapies against antibiotics-resistant Klebsiella pneumoniae

Журнал:

Human Vaccines & Immunotherapeutics

Рік:

2016

Мова:

english

Файл:

PDF, 890 KB

english, 2016

Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence

Mazor, Yariv, Sachsenmeier, Kris F., Yang, Chunning, Hansen, Anna, Filderman, Jessica, Mulgrew, Kathy, Wu, Herren, Dall’Acqua, William F.

Журнал:

Scientific Reports

Рік:

2017

Мова:

english

Файл:

PDF, 1.04 MB

english, 2017

An “Fc-Silenced” IgG1 Format With Extended Half-Life Designed for Improved Stability

Borrok, M. Jack, Mody, Neil, Lu, Xiaojun, Kuhn, Megan L., Wu, Herren, Dall'Acqua, William F., Tsui, Ping

Журнал:

Journal of Pharmaceutical Sciences

Рік:

2017

Мова:

english

Файл:

PDF, 1.28 MB

english, 2017

PET-guided evaluation and optimization of internalized antibody-drug conjugates targeting erythropoietin producing hepatoma A2 receptor

Jacobson, Orit, chen, haojun, Niu, Gang, Kiesewetter, Dale O, Li, Qing, Yang, Gengcheng, Cook, Kimberly, Xu, Lan, Dall'Acqua, William, Tsui, Ping, Peng, Li, Chen, Xiaoyuan

Журнал:

Journal of Nuclear Medicine

Рік:

2017

Мова:

english

Файл:

PDF, 1.12 MB

english, 2017

A high-throughput platform for population reformatting and mammalian expression of phage display libraries to enable functional screening as full-length IgG

Xiao, Xiaodong, Douthwaite, Julie A., Chen, Yan, Kemp, Ben, Kidd, Sara, Percival-Alwyn, Jennifer, Smith, Alison, Goode, Kate, Swerdlow, Bonnie, Lowe, David, Wu, Herren, Dall'Acqua, William F., Chowdhu

Журнал:

Rajan, Saravanan, Kierny, Michael R., Mercer, Andrew, Wu, Jincheng, Tovchigrechko, Andrey, Wu, Herren, Dall′Acqua, William F., Xiao, Xiaodong, Chowdhury, Partha S.

Рік:

2017

Мова:

english

Файл:

PDF, 1.55 MB

english, 2017

Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies

Журнал:

Communications Biology

Рік:

2018

Мова:

english

Файл:

PDF, 931 KB

english, 2018

Tumor uptake of pegylated diabodies: Balancing systemic clearance and vascular transport

Li, Qing, White, Jason B., Peterson, Norman C., Rickert, Keith W., Lloyd, Christopher O., Allen, Kevin L., Rosenthal, Kim, Gao, Xizhe, Wu, Herren, Dall'Acqua, William F., Jack Borrok, M., Tsui, Ping

Журнал:

Journal of Controlled Release

Рік:

2018

Мова:

english

Файл:

PDF, 1.42 MB

english, 2018

Enhancement of Immune Effector Functions by Modulating IgG’s Intrinsic Affinity for Target Antigen

Mazor, Yariv, Yang, Chunning, Borrok, M. Jack, Ayriss, Joanne, Aherne, Karen, Wu, Herren, Dall’Acqua, William F., Ho, Mitchell

Журнал:

PLoS ONE

Рік:

2016

Мова:

english

Файл:

PDF, 873 KB

english, 2016

Generation and Characterization of an IgG4 Monomeric Fc Platform

Shan, Lu, Colazet, Magali, Rosenthal, Kim L., Yu, Xiang-Qing, Bee, Jared S., Ferguson, Andrew, Damschroder, Melissa M., Wu, Herren, Dall’Acqua, William F., Tsui, Ping, Oganesyan, Vaheh, Korolev, Serge

Журнал:

PLoS ONE

Рік:

2016

Мова:

english

Файл:

PDF, 1.76 MB

english, 2016

The CEA/CD3-Bispecific Antibody MEDI-565 (MT111) Binds a Nonlinear Epitope in the Full-Length but Not a Short Splice Variant of CEA

Peng, Li, Oberst, Michael D., Huang, Jiaqi, Brohawn, Philip, Morehouse, Chris, Lekstrom, Kristen, Baeuerle, Patrick A., Wu, Herren, Yao, Yihong, Coats, Steven R., Dall’Acqua, William, Damschroder, Mel

Журнал:

PLoS ONE

Рік:

2012

Мова:

english

Файл:

PDF, 936 KB

english, 2012

Amber Suppression Coupled with Inducible Surface Display Identifies Cells with High Recombinant Protein Productivity

Chakrabarti, Lina, Zhuang, Li, Roy, Gargi, Bowen, Michael A., Dall’Acqua, William F., Hawley‐Nelson, Pam, Marelli, Marcello

Журнал:

Biotechnology and Bioengineering

Рік:

2018

Мова:

english

Файл:

PDF, 776 KB

english, 2018

Functional mimetic of the G-protein coupled receptor CXCR4 on a soluble antibody scaffold

Koksal, Adem C., Pennini, Meghan E., Marelli, Marcello, Xiao, Xiaodong, Dall’Acqua, William F.

Журнал:

Рік:

2019

Мова:

english

Файл:

PDF, 2.12 MB

english, 2019

Antibody Fragment F(ab′) 2 Targeting Caveolae-Associated Protein PV1 for Selective Kidney Targeting and Retention

Li, Qing, Peterson, Norman, Hanna, Richard N., Kuszpit, Kyle, White, Jason, Allen, Kevin L., Barnes, Arnita, Rickert, Keith W., Shan, Lu, Wu, Herren, Dall’Acqua, William F., Tsui, Ping, Borrok, M. Jac

Журнал:

Molecular Pharmaceutics

Рік:

2019

Мова:

english

Файл:

PDF, 1.22 MB

english, 2019

Development of a high yielding expression platform for the introduction of non-natural amino acids in protein sequences

Roy, Gargi, Reier, Jason, Garcia, Andrew, Martin, Tom, Rice, Megan, Wang, Jihong, Prophet, Meagan, Christie, Ronald, Dall’Acqua, William, Ahuja, Sanjeev, Bowen, Michael A, Marelli, Marcello

Журнал:

Рік:

2020

Файл:

PDF, 4.67 MB

2020

Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen

Wang, Bo, Yang, Chunning, Jin, Xiaofang, Du, Qun, Wu, Herren, Dall’Acqua, William, Mazor, Yariv

Журнал: